Carbofluorination of ??Bonds and Related Reactions Involving Tandem C?C/C?F Bond Formation
نویسندگان
چکیده
Due to the unique properties of C?F bonds, organofluorine compounds occupy a privileged space in pharmaceutical, agrochemical, and polymer industries. Carbofluorination reactions involve formation C?C bond, typically across ?-bond or another unsaturated functionality that is revealed upon situ activation. The design tailored substrates new catalyst systems has enabled carbofluorination chemistry emerge as promising manifold for synthesis fluorinated scaffolds. This review covers application nucleophilic electrophilic fluorinating reagents this chemistry, addition recently developed atom-economical using dual reagents.
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ژورنال
عنوان ژورنال: European Journal of Organic Chemistry
سال: 2023
ISSN: ['1434-193X', '1099-0690']
DOI: https://doi.org/10.1002/ejoc.202300017